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Rabbit Anti-PDE8A/Cy5.5 Conjugated antibody (bs-12587R-Cy5.5)
訂購熱線:400-901-9800
訂購郵箱:sales@www.ssxsbs.com
訂購QQ:  400-901-9800
技術支持:techsupport@www.ssxsbs.com
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-12587R-Cy5.5
英文名稱 Rabbit Anti-PDE8A/Cy5.5 Conjugated antibody
中文名稱 Cy5.5標記的磷酸二酯酶8A抗體
別    名 5''-cyclic phosphodiesterase 8A; cAMP specific cyclic nucleotide phosphodiesterase 8A; cAMP-specific cyclic nucleotide phosphodiesterase 8A; FLJ16150; High affinity cAMP specific and IBMX insensitive 3'5' cyclic phosphodiesterase 8A; High affinity cAMP-specific and IBMX-insensitive 3''; High-affinity cAMP-specific and IBMX-insensitive 3'5'-cyclic phosphodiesterase 8A; HsT19550; PDE 8A; PDE8A; PDE8A_HUMAN; Phosphodiesterase 8A; Phosphodiesterase8A; Weakly similar to 3'5' cyclic nucleotide phosphodiesterase; Weakly similar to 3'5'-cyclic-nucleotide phosphodiesterase.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉導  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 98-102kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PDE8A
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE8 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011]

Function:
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development.

Tissue Specificity:
Expressed in most tissues except thymus and peripheral blood leukocytes. Highest levels in testis, ovary, small intestine and colon.

Similarity:
Belongs to the cyclic nucleotide phosphodiesterase family.
PDE8 subfamily.
Contains 1 PAC (PAS-associated C-terminal) domain.
Contains 1 PAS (PER-ARNT-SIM) domain.

Database links:

Entrez Gene: 5151 Human

Entrez Gene: 18584 Mouse

Entrez Gene: 308776 Rat

Omim: 602972 Human

SwissProt: O60658 Human

SwissProt: O88502 Mouse

Unigene: 9333 Human

Unigene: 371577 Mouse

Unigene: 24771 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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