產品編號 | bs-12587R-Gold |
英文名稱 | Rabbit Anti-PDE8A/Gold Conjugated antibody |
中文名稱 | 膠體金標記的磷酸二酯酶8A抗體 |
別 名 | 5''-cyclic phosphodiesterase 8A; cAMP specific cyclic nucleotide phosphodiesterase 8A; cAMP-specific cyclic nucleotide phosphodiesterase 8A; FLJ16150; High affinity cAMP specific and IBMX insensitive 3'5' cyclic phosphodiesterase 8A; High affinity cAMP-specific and IBMX-insensitive 3''; High-affinity cAMP-specific and IBMX-insensitive 3'5'-cyclic phosphodiesterase 8A; HsT19550; PDE 8A; PDE8A; PDE8A_HUMAN; Phosphodiesterase 8A; Phosphodiesterase8A; Weakly similar to 3'5' cyclic nucleotide phosphodiesterase; Weakly similar to 3'5'-cyclic-nucleotide phosphodiesterase. |
規格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領域 | 細胞生物 信號轉導 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應 | (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) |
產品應用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 98-102kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human PDE8A |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產品介紹 |
background: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE8 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011] Function: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development. Tissue Specificity: Expressed in most tissues except thymus and peripheral blood leukocytes. Highest levels in testis, ovary, small intestine and colon. Similarity: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily. Contains 1 PAC (PAS-associated C-terminal) domain. Contains 1 PAS (PER-ARNT-SIM) domain. Database links: Entrez Gene: 5151 Human Entrez Gene: 18584 Mouse Omim: 602972 Human SwissProt: O60658 Human SwissProt: O88502 Mouse Unigene: 9333 Human Unigene: 371577 Mouse Unigene: 24771 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
1、抗體溶解方法 | |
2、抗體修復方式 | |
3、常用試劑的配制 | |
4、免疫組化操作步驟 | |
5、免疫組化問題解答 | |
6、Western Blotting 操作步驟 | |
7、Western Blotting 問題解答 | |
8、關于肽鏈的設計 | |
9、多肽的溶解與保存 | |
10、酶標抗體效價測定程序 | |