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Rabbit Anti-SHOX2/BF488 Conjugated antibody (bs-17471R-BF488)
訂購熱線:400-901-9800
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訂購QQ:  400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-17471R-BF488
英文名稱 Rabbit Anti-SHOX2/BF488 Conjugated antibody
中文名稱 BF488標記的身材矮小同源盒基因SHOX2抗體
別    名 Homeobox protein Og12X; OG 12; OG 12X; OG12; OG12X; OGI 2X; OGI2X; Paired related homeobox protein SHOT; Paired-related homeobox protein SHOT; Short stature homeobox 2; Short stature homeobox homolog; Short stature homeobox protein 2; SHOT; SHOX 2; SHOX homologous gene on chromosome 3; SHOX2; SHOX2_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  發育生物學  信號轉導  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, Cat, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 35kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SHOX2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene is a member of the homeobox family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeobox genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeobox genes. This locus represents a pseudoautosomal homeobox gene that is thought to be responsible for idiopathic short stature, and it is implicated in the short stature phenotype of Turner syndrome patients. This gene is considered to be a candidate gene for Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]

Function:
May be a growth regulator and have a role in specifying neural systems involved in processing somatosensory information, as well as in face and body structure formation.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in heart, skeletal muscle, liver, lung, bone marrow fibroblast, pancreas and placenta.

Similarity:
Belongs to the paired homeobox family. Bicoid subfamily.
Contains 1 homeobox DNA-binding domain.

Database links:

Entrez Gene: 6474 Human

Entrez Gene: 20429 Mouse

Entrez Gene: 25546 Rat

Omim: 602504 Human

SwissProt: O60902 Human

SwissProt: P70390 Mouse

SwissProt: O35750 Rat

Unigene: 55967 Human

Unigene: 39093 Mouse

Unigene: 11258 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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