| 產(chǎn)品編號(hào) | bsm-63294R |
| 英文名稱 | phospho-Alpha synuclein (Y125) Recombinant Rabbit mAb |
| 中文名稱 | 磷酸化核突觸蛋白α重組兔單抗 |
| 別 名 | Alpha synuclein; alphaSYN; NACP; PARK1; PARK4; Parkinson disease familial 1; SNCA; SYN; Synuclein alpha 140. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號(hào) | 2E7 |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 14 kDa |
| 檢測(cè)分子量 | 18 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human alpha Synuclein around the phosphorylation site of Y125: NEA-pY-EM |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. SWISS: P37840 Gene ID: 6622 Synuclein 包括α-Synuclein，β-Synuclein 和γ-Synuclein 是神經(jīng)細(xì)胞中富含的前突觸蛋白。α-Synuclein，Alzheimer’(AD)病淀粉樣蛋白沉積的成份之一，集中分布在神經(jīng)細(xì)胞的包體和突觸。在帕金森病人中發(fā)現(xiàn)有α-Synuclein的變異型，而γ-Synuclein與軸突病理學(xué)有關(guān)。 此抗體將為L(zhǎng)ewy小體癡呆癥、Parkinson癥、AD和其它一些神經(jīng)性疾病提供有用的病理診斷。 |
