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phospho-NBN (S343) Recombinant Rabbit mAb (bsm-63112R)  
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產品編號 bsm-63112R
英文名稱 phospho-NBN (S343) Recombinant Rabbit mAb
中文名稱 磷酸化DNA修復蛋白NBS1重組兔單抗
別    名 Cell cycle regulatory protein P95; NBN; NBS; NIBRIN; NIJMEGEN BREAKAGE syndrome protein 1; p95-NBS1.  
抗體來源 Rabbit
克隆類型 Recombinant
克 隆 號 9F2
交叉反應 Human
產品應用 WB=1:1000-1:2000,ICC/IF=1:50-1:200,IP=1:20-1:50
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 85 kDa
檢測分子量 95
性    狀 Liquid
免 疫 原 A synthesized peptide derived from human p95 NBS1 around the phosphorylation site of S343: SL-pS-QG 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
保存條件 Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The MRN complex is involved in the repair of DNA double-strand breaks (DSBs) via homologous recombination (HR), an error-free mechanism which primarily occurs during S and G2 phases.

SWISS:
O60934

Gene ID:
4683

NBS1蛋白可與Mre11和Rad50蛋白形成一個Mre11-Rad50-NBS1復合物,在DNA的復制和DNA雙鏈斷裂的修復等過程中起重要作用。
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