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S100A4 Recombinant Rabbit mAb (bsm-55522R)  
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25ul/800.00元
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產品編號 bsm-55522R
英文名稱 S100A4 Recombinant Rabbit mAb
中文名稱 S100鈣結合蛋白A4重組兔單抗
別    名 18A2; 42A; CAPL; FSP1; MTS1; P9KA; PEL98; S100 calcium binding protein A4  
抗體來源 Rabbit
克隆類型 Recombinant
克 隆 號 SB100
交叉反應 Human,Mouse,Rat
產品應用 WB=1: 500-1: 2000,IHC-P=1: 800-1: 1600,IHC-F=1: 800-1: 1600,IF=1: 800-1: 1600
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 12 kDa
檢測分子量 12
性    狀 Liquid
免 疫 原 Recombinant Mouse S100A4 protein 
亞    型 IgG
純化方法 Affinity Purification
緩 沖 液 PBS with 100 μg/ml BSA,0.15% ProClin300 and 50% glycerol.
保存條件 Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis.

SWISS:
P07091

Gene ID:
20198

S100A4屬于鈣離子結合蛋白S100蛋白家族,參與細胞骨架及細胞膜的相互作用、鈣離子信號傳遞和細胞生長及分化等,在細胞內、外均可發揮作用,增加腫瘤細胞的運動、侵襲能力,降低細胞間黏附力,重塑細胞外基質,促進細胞異常增生及血管生成,被稱為轉移促進基因。
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