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PSD95 Recombinant Rabbit mAb (bsm-60886R)  
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25ul/800.00元
50ul/1400.00元
100ul/2500.00元
大包裝/詢價

產品編號 bsm-60886R
英文名稱 PSD95 Recombinant Rabbit mAb
中文名稱 突觸后密度蛋白95重組兔單抗
別    名 Discs large homolog 4; Disks large homolog 4; DLG 4; DLG4; DLG4_HUMAN; FLJ97752; FLJ98574; Human post synaptic density protein 95; Human post-synaptic density protein 95; Post synaptic density protein 95; Postsynaptic density protein 95; PSD 95; PSD-95; SAP 90; SAP-90; SAP90; Synapse associated protein 90; Synapse-associated protein 90; Tax interaction protein 15.  
抗體來源 Rabbit
克隆類型 Recombinant
克 隆 號 1F1
交叉反應 Mouse,Rat
產品應用 WB=1:200-1000,IHC-P=1:50-200,IHC-F=1:50-200,IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 80 kDa
檢測分子量
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse PSD95 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

SWISS:
Q62108

Gene ID:
13385

該蛋白質PSD95能夠幫助建立神經突觸的架構,并且促成突觸其他部分的成熟,例如加強目標細胞上的glutamate受體的聚集、增加樹突棘(dendritic spines)的數量和大小以及增加神經傳導物質glutamate (谷氨酸鹽)釋放的量。這種蛋白質與阿滋海默癥有關。
產品圖片
25 ug total protein per lane of various lysates (see on figure) probed with PSD95 monoclonal antibody, unconjugated (bsm-60886R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
Paraformaldehyde-fixed, paraffin embedded Rat eye; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with PSD95 Monoclonal Antibody, Unconjugated(bsm-60886R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Mouse eye; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with PSD95 Monoclonal Antibody, Unconjugated(bsm-60886R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Rat Cerebellum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with PSD95 Monoclonal Antibody, Unconjugated(bsm-60886R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Mouse Cerebellum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with PSD95 Monoclonal Antibody, Unconjugated(bsm-60886R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
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