| 產(chǎn)品編號 | D51711 |
| 英文名稱 | Apilimod dimesylate |
| 中文名稱 | |
| 別 名 | PIKfyve/IL-12/IL-23抑制劑 |
| CAS | 870087-36-8 |
| 理論分子量 | 610.7 kDa |
| 檢測分子量 | |
| 性 狀 | Lyophilized |
| 保存條件 | Store in dry, dark place for one year. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
Apilimod dimesylate, also known as STA-5326, is a IL-12/IL-23 inhibitor. Apilimod inhibits IL-12 and IL-23 production - cytokines that are involved in autoimmune diseases - through the prevention of nuclear translocation of c-Rel. Synta Pharmaceuticals Corp is developing apilimod for the potential treatment of Crohn's disease (CD) and other autoimmune diseases. Preclinical studies demonstrated the successful inhibition of IL-12 and IL-23 production by the drug. |
