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RAIDD Recombinant Rabbit mAb (bsm-61003R)  
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25ul/800.00元
50ul/1400.00元
100ul/2500.00元
大包裝/詢價

產品編號 bsm-61003R
英文名稱 RAIDD Recombinant Rabbit mAb
中文名稱 CASP2凋亡相關蛋白重組兔單抗
別    名 CASP2 and RIPK1 domain containing adaptor with death domain; Caspase and RIP adapter with death domain; Caspase and RIP adaptor with death domain; CRADD; CRADD_HUMAN; Death adaptor molecule RAIDD; Death domain containing protein CRADD; Death domain-containing protein CRADD; MGC9163; RIP associated ICH1/CED3 homologous protein with death domain; RIP associated protein with a death domain; RIP-associated ICH1/CED3-homologous protein with death domain; RIP-associated protein with a death domain.  
抗體來源 Rabbit
克隆類型 Recombinant
克 隆 號 9D15
交叉反應 Human
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 22 kDa
檢測分子量
細胞定位 細胞核 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 A synthesized peptide derived from human CRADD: 150-199/199 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex.

Subunit:
Interacts with LRDD.

Tissue Specificity:
Constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney.

Similarity:
Contains 1 CARD domain. Contains 1 death domain.

Database links:

Entrez Gene: 8738 Human

Entrez Gene: 12905 Mouse

Entrez Gene: 314756 Rat

Omim: 603454 Human

SwissProt: P78560 Human

SwissProt: O88843 Mouse

Unigene: 38533 Human

Unigene: 591016 Human



產品圖片
25 ug total protein per lane of various lysates (see on figure) probed with RAIDD monoclonal antibody, unconjugated (bsm-61003R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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