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DUSP1 Recombinant Rabbit mAb (bsm-52770R)  
~~~促銷,代碼KT202504~~~
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50ul/1400.00元
100ul/2500.00元
大包裝/詢價
產品編號 bsm-52770R
英文名稱 DUSP1 Recombinant Rabbit mAb
中文名稱 絲裂原活化蛋白激酶磷酸酶-1重組兔單抗
別    名 Mitogen activated protein kinase phosphatase 1; CL 100; CL100; Dual Specificity Phosphatase 1; Dual specificity protein phosphatase 1; Dual specificity protein phosphatase hVH1; DUSP 1; DUSP-1; EC 3.1.3.16; EC 3.1.3.48; HVH 1; HVH1; MAP kinase phosphatase 1; MKP 1; MKP1; MKP-1; Protein tyrosine phosphatase CL100; PTPN 10; PTPN10; Serine/threonine specific protein phosphatase; VH 1; VH1; 3ch134; Mkp1; Ptpn16.  
研究領域 腫瘤  免疫學  信號轉導  細胞凋亡  轉錄調節(jié)因子  
抗體來源 Rabbit
克隆類型 Recombinant
克 隆 號 4G7
交叉反應 (predicted: Human,Mouse,Rat)
產品應用 WB=1:500-1000,IHC-P=1:100-500,IHC-F=1:50-200,IF=1:100-500,Flow-Cyt=1:50-100
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 39 kDa
檢測分子量
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DUSP1: 100-160/367 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues.

SWISS:
P28562

Gene ID:
1843

Database links:

Entrez Gene: 1843 Human

Entrez Gene: 19252 Mouse

Entrez Gene: 114856 Rat

Omim: 600714 Human

SwissProt: P28562 Human

SwissProt: P28563 Mouse

SwissProt: Q64623 Rat

Unigene: 171695 Human

Unigene: 239041 Mouse

Unigene: 98260 Rat



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