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SPINK1 Recombinant Rabbit mAb (bsm-60323R)  
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產品編號 bsm-60323R
英文名稱 SPINK1 Recombinant Rabbit mAb
中文名稱 腫瘤相關胰蛋白酶抑制劑1重組兔單抗
別    名 ISK1_HUMAN; Serine protease inhibitor Kazal-type 1; Pancreatic secretory trypsin inhibitor; PCTT; PSTI; TCP; TATI; Serine protease inhibitor Kazal type 1; Spink 3; Spink3; Tumor-associated trypsin inhibitor(TATI);  
抗體來源 Rabbit
克隆類型 Recombinant
克 隆 號 E5F9
交叉反應 Human
產品應用 IHC-P=1:50-200,IHC-F=1:50-200,IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 6.2 kDa
檢測分子量
細胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 A synthesized peptide derived from human SPINK1: 1-79/79 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis. [provided by RefSeq, Oct 2008]

Subcellular Location:
Secreted.

Database links:

Entrez Gene: 6690 Human

SwissProt: P00995 Human



絲氨酸蛋白酶抑制劑因子Kazal 1型(SPINK1)是蛋白酶抑制劑家族的成員之一。因其在卵巢癌,胰腺癌,肝細胞癌,結直腸癌,前列腺癌等惡性腫瘤的發生、發展及預后中發揮重要作用,因此,SPINK1作為一種腫瘤標志物的臨床應用受到廣泛關注。
產品圖片
Tissue: Human pancreas Section type: Formalin fixed & Paraffin -embedded section Retrieval method: High temperature and high pressure Retrieval buffer: Tris/EDTA buffer, pH 9.0 Primary ab dilution: 1:1000 Primary ab incubation condition: 1 hour at room temperature Counter stain: Hematoxylin Comment: Color brown is the positive signal for bsm-60323R
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