| 產品編號 |
bsk11064 |
| 英文名稱 |
Human IgM ELISA Kit
|
| 中文名稱 |
人免疫球蛋白M酶聯免疫試劑盒 |
| 別 名 |
HUMAN IGM PROTEIN; IgM from human serum; Human IgM Purified; Human IgM Protein (Native); human immunoglobulin
|
| 種 屬 |
Human |
| 線性范圍 |
15.60 - 1,000 ng/mL |
| 應用范圍 |
S/P/CC |
| 檢測限 |
7 ng/mL |
| 適用樣品基質 |
cell culture supernates, serum, and plasma. |
| 保存條件 |
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.). |
| 注意事項 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產品介紹 |
IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences.
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