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SEC62 Rabbit pAb (bs-19619R)  
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產品編號 bs-19619R
英文名稱 SEC62 Rabbit pAb
中文名稱 轉運蛋白SEC62抗體
別    名 Dtrp1; FLJ32803; hTP-1; HTP1; Membrane protein SEC62, S.cerevisiae, homolog of; OTTHUMP00000213390; sec62; SEC62 homolog(S. cerevisiae); SEC62_HUMAN; TLOC1; TP-1; Translocation protein 1; Translocation protein sec62.  
研究領域 細胞生物  信號轉導  轉運蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human,Mouse,Rat (predicted: Rabbit,Pig,Sheep,Cow,Dog,Horse)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 46 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SEC62: 251-350/399 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008]

Function:
Required for preprotein translocation.

Subunit:
Part of a complex that contains SEC61, SEC62 and SEC63. Interacts with SEC61B.

Subcellular Location:
Endoplasmic reticulum membrane.

Similarity:
Belongs to the SEC62 family.

SWISS:
Q99442

Gene ID:
7095

Database links:

Entrez Gene: 7095 Human

Entrez Gene: 69276 Mouse

Entrez Gene: 294912 Rat

Omim: 602173 Human

SwissProt: Q99442 Human

SwissProt: Q8BU14 Mouse

Unigene: 592561 Human



產品圖片
Sample: Lane 1: Thymus (Mouse) Lysate at 40 ug Lane 2: Uterus (Mouse) Lysate at 40 ug Lane 3: Thymus (Rat) Lysate at 40 ug Lane 4: A431 (Human) Cell Lysate at 30 ug Primary: Anti- SEC62 (bs-19619R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 46 kD Observed band size: 48 kD
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