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NDUFS6 Rabbit pAb (bs-19092R)  
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產品編號 bs-19092R
英文名稱 NDUFS6 Rabbit pAb
中文名稱 NDUFS6蛋白抗體
別    名 BC059730; CI 13kA; CI 13kD A; CI-13kD-A; CI13KDA; Complex I 13kD A; Complex I 13kDa subunit A; Complex I mitochondrial respiratory chain 13 kD subunit; Complex I-13kD-A; IP13; MGC107676; NADH dehydrogenase(ubiquinone) Fe-S protein 6, 13kDa(NADH coenzyme Q  
研究領域 腫瘤  細胞生物  信號轉導  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human (predicted: Mouse,Rat,Cow,Dog,Horse)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 11 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NDUFS6: 81-124/124 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a subunit of the NADH:ubiquinone oxidoreductase (complex I), which is the first enzyme complex in the electron transport chain of mitochondria. This complex functions in the transfer of electrons from NADH to the respiratory chain. The subunit encoded by this gene is one of seven subunits in the iron-sulfur protein fraction. Mutations in this gene cause mitochondrial complex I deficiency, a disease that causes a wide variety of clinical disorders, including neonatal disease and adult-onset neurodegenerative disorders.[provided by RefSeq, Oct 2009]

Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

Subcellular Location:
Mitochondrion inner membrane.

Similarity:
Belongs to the complex I NDUFS6 subunit family.

SWISS:
O75380

Gene ID:
4726

Database links:

Entrez Gene: 4726 Human

Entrez Gene: 407785 Mouse

Entrez Gene: 29478 Rat

Omim: 603848 Human

SwissProt: O75380 Human

SwissProt: P52503 Mouse

SwissProt: P52504 Rat

Unigene: 408257 Human

Unigene: 29897 Mouse

Unigene: 154403 Rat



產品圖片
Sample: Lane 1: Hela (Human) Cell Lysate at 30 ug Lane 2: U937 (Human) Cell Lysate at 30 ug Primary: Anti-NDUFS6 (bs-19092R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 11 kD Observed band size: 15 kD
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