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Cytochrome P450 2B1 Rabbit pAb (bs-14177R)  
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產品編號 bs-14177R
英文名稱 Cytochrome P450 2B1 Rabbit pAb
中文名稱 細胞色素P450 2B1抗體
別    名 Cyp2b 1; Cyp2b 2; Cyp2b1; Cyp2b2; Cypbe; Cytochrome P450 2B1+2B2; Cype; CYPIIB1; CYPIIB2; Cytochrome P 450b; Cytochrome P 450b type e; Cytochrome P 450e M; Cytochrome P450 2B1; Cytochrome P450 2B2; Cytochrome P450 family 2 subfamily b polypeptide 1; Cytoc  
研究領域 腫瘤  心血管  細胞生物  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Mouse,Rat)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 56 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from Rat Cytochrome P450 2B1: 301-400/491 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 phenobarbitol-inducible member of the p450 xenobiotic-inducible superfamily involved in hydroxylation of decanoic and other fatty acids [RGD, Feb 2006]

Function:
The Cytochrome P450 superfamily of enzymes is one of three enzyme systems which metabolize the fatty acid arachadonic acid (AA) to regulators of vascular tone. P450 enzymes are monooxygenase enzymes which require several co-factors such as nicotinamide adenine dinucleotide phosphate (NADPH) and P450 reductase. There are over 200 known genes which encode P450s. Epoxygenases are those P450s which metabolize AA to epoxyeicosatrienoic acid (EETs) and omega-hydroxylases are those P450s which produce 19- and 20-hydroxyeicosatetraenoic acids (19- and 20-HETE). As well as fatty acid metabolism, P450s also metabolize many drugs and toxins. Cytochrome P450 3A4 is abundantly expressed in liver and small intestine and is inducible by barbiturates, glucocorticoids and rifampicin.

Subcellular Location:
Membrane bound, endoplasmic reticulum

Post-translational modifications:
Phosphorylation is accompanied by a decrease in enzyme activity.

Similarity:
Belongs to the cytochrome P450 family.

SWISS:
P04167

Gene ID:
361523

Database links:

Entrez Gene: 24300 Rat

Entrez Gene: 361523 Rat

SwissProt: P00176 Rat

SwissProt: P04167 Rat



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