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CLDND1 Rabbit pAb (bs-6683R)  
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產品編號 bs-6683R
英文名稱 CLDND1 Rabbit pAb
中文名稱 膜蛋白CLDND1抗體
別    名 C3orf4; Chromosome 3 open reading frame 4; Claudin domain containing 1; Claudin domain containing 1 protein; Membrane protein GENX3745; CLDN1_HUMAN.  
研究領域 細胞生物  神經生物學  細胞粘附分子  細胞表面分子  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human (predicted: Mouse,Rat,Sheep,Cow,Dog,Horse)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 29 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CLDND1: 201-253/253 
亞    型
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 CLDND1 is a 253 amino acid multi-pass membrane protein that is expressed at high levels in adult brain and at lower levels in adult heart. Existing as two alternatively spliced isoforms, CLDND1 is encoded by a gene that maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.

Subcellular Location:
Membrane; Multi pass membrane protein.

Tissue Specificity:
Widely distributed in the adult CNS with highest expression in the corpus callosum, caudate nucleus, cerebral cortex, medulla, putamen, spinal cord, substantia nigra and subthalamic nucleus. Weak expression was detected in the adult heart.

Similarity:
Belongs to the PMP-22/EMP/MP20 family.

SWISS:
Q9NY35

Gene ID:
56650

Database links:

Entrez Gene: 56650 Human

Entrez Gene: 224250 Mouse

Entrez Gene: 288182 Rat

SwissProt: Q9NY35 Human

SwissProt: Q9CQX5 Mouse

SwissProt: Q5XIN0 Rat



產品圖片
Sample: Siha(Human) Cell Lysate at 30 ug Primary: Anti- CLDND1 (bs-6683R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 29 kD Observed band size: 30 kD
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