| 產品編號 | bs-6300R |
| 英文名稱 | TEM7R Rabbit pAb |
| 中文名稱 | 腫瘤血管內皮標記相關蛋白質7抗體 |
| 別 名 | Tumor endothelial marker 7 related protein; Plexin domain containing 2; Plexin domain containing protein 2; Plexin domain-containing protein 2; PLXDC 2; plxdc2; PXDC2_HUMAN; TEM7R; Tumor endothelial marker 7-related protein. |
| 研究領域 | 腫瘤 血管內皮細胞 腫瘤細胞生物標志物 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Dog,Horse) |
| 產品應用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 56 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TEM7R.: 101-200/529 <Extracellular> |
| 亞 型 | |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產品介紹 |
TEM7R also known as PLXDC2 is a 529 amino acid single-pass type I membrane protein containing one PSI domain and belonging to the plexin family. Localizing to membrane, TEM7R is expressed in endothelial cells of the stroma, as well as in limbs, lung buds, developing heart, spinal cord and dorsal root ganglia. TEM7R interacts with cortactin and may play a role in tumor angiogenesis. Existing as three alternatively spliced isoforms, the gene encoding TEM7R maps to human chromosome 10p12.31. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5% of total DNA in cells and encodes nearly 1,200 genes. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria. Function: May play a role in tumor angiogenesis. Subunit: Interacts with CTTN. Subcellular Location: Membrane; Single-pass type I membrane protein Tissue Specificity: Expressed in the endothelial cells of the stroma but not in the endothelial cells of normal colonic tissue. Similarity: Belongs to the plexin family. Contains 1 PSI domain. SWISS: Q6UX71 Gene ID: 84898 Database links: Entrez Gene: 84898 Human Entrez Gene: 67448 Mouse Omim: 606827 Human SwissProt: Q6UX71 Human SwissProt: Q9DC11 Mouse Unigene: 658134 Human Unigene: 313938 Mouse Unigene: 394655 Mouse |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
