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ADCY4 Rabbit pAb (bs-3921R)  
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50ul/1180.00元
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產品編號 bs-3921R
英文名稱 ADCY4 Rabbit pAb
中文名稱 腺苷酸環化酶4抗體
別    名 AC4; Adenylate cyclase 4; adenylate cyclase type 4; Adenylate cyclase type IV; Adenylyl cyclase; ATP pyrophosphate lyase 4; ATP pyrophosphate lyase; ADCY4_HUMAN.  
研究領域 腫瘤  細胞生物  免疫學  信號轉導  生長因子和激素  轉錄調節因子  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human (predicted: Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 120 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ADCY4: 851-1077/1077 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The ADCY4 gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. Alternative splicing results in transcript variants.

Function:
This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity).

Subcellular Location:
Membrane; Multi-pass membrane protein.

Similarity:
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Contains 2 guanylate cyclase domains.

SWISS:
Q8NFM4

Gene ID:
196883

Database links:
UniProtKB/Swiss-Prot: Q8NFM4.1

產品圖片
25 ug total protein per lane of various lysates (see on figure) probed with ADCY4 polyclonal antibody, unconjugated (bs-3921R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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