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NKp80 Rabbit pAb (bs-2681R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產品編號 bs-2681R
英文名稱 NKp80 Rabbit pAb
中文名稱 細胞毒性受體NK-p80抗體
別    名 C type lectin domain family 5 member C; CLEC5C; killer cell lectin like receptor F1; Killer cell lectin like receptor subfamily F member 1; KLRF 1; Lectin like receptor F1; MGC119907; MGC119908; MGC119909; ML; NKp80; KLRF1_HUMAN.  
研究領域 免疫學  自然殺傷細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 27 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KLRF1: 35-130/232 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 KLRF1, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on nearly all natural killer (NK) cells and stimulates their cytoxicity and cytokine release (Kuttruff et al., 2009 [PubMed 18922855]).[supplied by OMIM, Oct 2009]

Function:
Involved in the natural killer (NK)-mediated cytolysis of PHA-induced lymphoblasts.

Subunit:
Homodimer.

Subcellular Location:
Membrane; Single-pass type II membrane protein (Potential).

Tissue Specificity:
Strongly expressed in peripheral blood leukocytes and spleen, with weaker expression in lymph node and adult liver, and no expression detected in bone marrow, thymus, and fetal liver. Not expressed in brain, heart, placenta, lung, kidney, skeletal muscle, and pancreas. Within peripheral blood leukocyte and immunocyte cell lines, expression was predominant in NK cells but was also detected in monocytes.

Similarity:
Contains 1 C-type lectin domain.

SWISS:
Q9NZS2

Gene ID:
51348

Database links:

Entrez Gene: 51348 Human

Omim: 605029 Human

SwissProt: Q9NZS2 Human



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