| 產品編號 | bs-1876R |
| 英文名稱 | EP3/PTGER3 Rabbit pAb |
| 中文名稱 | 前列腺素E受體3抗體 |
| 別 名 | EP 3; EP3; EP3 I; EP3 II; EP3 III; EP3 IV; Ep3 prostanoid receptor; Ep3 receptor; EP3 subtype; EP3e; HGNC:9595; MGC141828; MGC141829; MGC27302; PE2R3_HUMAN; PGE receptor EP3 subtype; PGE2 R; PGE2 receptor EP3 subtype; PGE2-R; PGE2R; Pgerep3; Prostaglandin |
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Specific References (2) | bs-1876R has been referenced in 2 publications.
[IF=4.556] Li?H et al. Meloxicam Improves Cognitive Impairment of Diabetic Rats through COX2-PGE2-EPs-cAMP/pPKA Pathway. Mol Pharm. 2018 Sep 4;15(9):4121-4131. WB ; Rat.
[IF=2.253] Chen Z et al. Seasonal expressions of prostaglandin E synthases and receptors in the prostate of the wild ground squirrel (Spermophilus dauricus). Prostaglandins and Other Lipid Mediators 148 (2020) 106412. IHC-P ; squirrel.
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| 研究領域 | 信號轉導 G蛋白偶聯受體 新陳代謝 G蛋白信號 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | Mouse (predicted: Rat) |
| 產品應用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 43 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human EP3: 51-150/390 <Cytoplasmic> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產品介紹 |
The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. Function: Receptor for prostaglandin E2 (PGE2); the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction in uterine smooth muscle. The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G-I proteins, and to an elevation of intracellular calcium. The various isoforms have identical ligand binding properties but can interact with different second messenger systems. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in small intestine, heart, pancreas, gastric fundic mucosa, mammary artery and pulmonary vessels. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: P43115 Gene ID: 5733 Database links: Entrez Gene: 5733 Human Entrez Gene: 19218 Mouse Omim: 176806 Human SwissProt: P43115 Human SwissProt: P30557 Mouse Unigene: 445000 Human Unigene: 30424 Mouse Unigene: 10361 Rat |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
