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FSH beta Rabbit pAb (bs-1536R)  
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產品編號 bs-1536R
英文名稱 FSH beta Rabbit pAb
中文名稱 促卵泡刺激素抗體
別    名 Follicle Stimulating Hormone; Follicle stimulating hormone beta polypeptide; Follicle stimulating hormone beta subunit; Follitropin beta chain; Follitropin beta chain precursor; Follitropin subunit beta; FSH B; FSH-B; FSH-beta; FSHB; FSHbeta.  
Specific References  (2)     |     bs-1536R has been referenced in 2 publications.
[IF=3.484] Yang H et al. Genome-Wide Analysis and Function Prediction of Long Noncoding RNAs in Sheep Pituitary Gland Associated with Sexual Maturation. Genes (Basel). 2020 Mar 17;11(3). pii: E320.  IF ;  sheep.  
[IF=3.191] Zheng J et al. Pituitary Transcriptomic Study Reveals the Differential Regulation of lncRNAs and mRNAs Related to Prolificacy in Different FecB Genotyping Sheep. Genes (Basel). 2019 Feb 18;10(2).  IF ;  Sheep.  
研究領域 免疫學  生長因子和激素  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human (predicted: Rabbit,Pig,Sheep,Cow,GuineaPig,Horse)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 12 kDa
檢測分子量
細胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FSHB: 61-98/129 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. All of these glycoproteins consist of an identical alpha subunit and a hormone-specific beta subunit. This gene encodes the beta subunit of follicle-stimulating hormone. In conjunction with luteinizing hormone, follicle-stimulating hormone induces egg and sperm production. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

Function:
Stimulates development of follicle and spermatogenesis in the reproductive organs.

Subunit:
Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin.

Subcellular Location:
Secreted.

DISEASE:
Defects in FSHB are a cause of isolated follicle-stimulating hormone deficiency (IFSHD) [MIM:229070]. Selective follicle-stimulating hormone deficiency is an uncommon cause of infertility, producing amenorrhea and hypogonadism in women and oligo or azoospermia with normal testosterone levels in normally virilised men.

Similarity:
Belongs to the glycoprotein hormones subunit beta family.

SWISS:
P01225

Gene ID:
2488

Database links:

Entrez Gene: 2488 Human

Entrez Gene: 100008946 Rabbit

Omim: 136530 Human

SwissProt: P01225 Human

SwissProt: Q6IY73 Rabbit

Unigene: 36975 Human



促卵泡激素與黃體生成素統稱促性腺激素具有促進卵泡發育成熟作用,與黃體生成素一起促進雌激素分泌.
產品圖片
Sample: Hela(Human) Cell Lysate at 30 ug Primary: Anti-FSH beta (bs-1536R) at 1/500 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 12 kD Observed band size: 22/27 kD
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