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IL 7 receptor alpha Recombinant Rabbit mAb (bsm-61095R)  
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25ul/800.00元
50ul/1400.00元
100ul/2500.00元
大包裝/詢價

產品編號 bsm-61095R
英文名稱 IL 7 receptor alpha Recombinant Rabbit mAb
中文名稱 白細胞介素-7受體a(CD127)重組兔單抗
別    名 IL-7Rα; IL-7Ra; Interleukin-7 receptor subunit alpha; CD 127; CD127; CD127 antigen; CDW127; IL 7R alpha; IL 7R; IL-7 receptor subunit alpha; IL-7R subunit alpha; IL-7R-alpha; IL7RA; IL7Ralpha; Interleukin 7 receptor alpha chain; Interleukin 7 receptor; Interleukin 7 receptor isoform H5 6; IL7RA_HUMAN.  
抗體來源 Rabbit
克隆類型 Recombinant
克 隆 號 17E3
交叉反應 Human,Mouse (predicted: Rat)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 50 kDa
檢測分子量
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 A synthesized peptide derived from human IL 7 receptor alpha: 350-400 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID).

SWISS:
P16871

Gene ID:
3575

產品圖片
25 ug total protein per lane of various lysates (see on figure) probed with IL 7 receptor alpha monoclonal antibody, unconjugated (bsm-61095R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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